Styled Component styles are disabled in Chrome DevTools

It's because styled-components injects styles through the CSSOM API, which the Dev Tools in Chrome (and every other browser AFAIK) can't handle. See this ticket: https://bugs.chromium.org/p/chromium/issues/detail?id=387952

Note that this is only true when styled-components is in production mode, i.e. process.env.NODE_ENV is set to "production". As long as you aren't in production mode, styled-components should generate normal <style> tags, which you can interact with through the Dev Tools.

In v4.1.0 it's possible to provide SC_DISABLE_SPEEDY flag to disable styles injection with CSSOM insertRule.

More details
https://www.styled-components.com/releases#v4.1.0
https://github.com/styled-components/styled-components/pull/2185