Write new select2 option tags to local database in express

You can use select2:select and select2:unselect event for this.

var dataBase = [{
    id: 0,
    text: 'Maths'
  },
  {
    id: 1,
    text: 'English'
  },
  {
    id: 2,
    text: 'Biology'
  },
  {
    id: 3,
    text: 'Chemistry'
  },
  {
    id: 4,
    text: 'Geography'
  }
];

$(document).ready(function() {
  $('.select2-container').select2({
    data: dataBase,
    placeholder: 'Start typing to add subjects...',
    width: 'style',
    multiple: true,
    tags: true,
    createTag: function(tag) {
      return {
        id: tag.term,
        text: tag.term,
        isNew: true
      };
    },
    tokenSeparators: [',', '.']
  })
  $(document).on("select2:select select2:unselect", '.select2-container', function(e) {
    var allSelected = $('.select2-container').val();
    console.log('All selected ' + allSelected);

    var lastModified = e.params.data.id;
    console.log('Last Modified ' + lastModified);

    var dbIdArray = dataBase.map((i) => i.id.toString());
    var allTagged = $('.select2-container').val().filter((i) => !(dbIdArray.indexOf(i) > -1))
    console.log('All Tagged ' + allTagged);
  });
});

.select2-container {
  width: 200px;
}

<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.3.1/jquery.min.js"></script>
<script src="https://cdnjs.cloudflare.com/ajax/libs/select2/4.0.6-rc.0/js/select2.min.js"></script>
<link href="https://cdnjs.cloudflare.com/ajax/libs/select2/4.0.6-rc.0/css/select2.min.css" rel="stylesheet" />

<select class="select2-container"></select>

On your server-side, you can have an api that maintains and returns the tag array. If you want the array to persist even after server shutdown, you can store the tags array in a database.

Server side:

let dataBase = [
{ id: 0, text: 'Maths'},
{ id: 1, text: 'English'},
{ id: 2, text: 'Biology'},
{ id: 3, text: 'Chemistry'},
{ id: 4, text: 'Geography'}
];
//Assuming you have a nodejs-express backend
app.get('/tags', (req,res) => {
res.status(200).send({tags: dataBase});
} );

Client Side:

$(document).ready(function() {
dataBase=[];
$.get("YOUR_SERVER_ADDRESS/tags", function(data, status){
console.log("Data: " + data + "\nStatus: " + status);
dataBase = data;
});

$('.select2-container').select2({
    data: dataBase,
    placeholder: 'Start typing to add subjects...',
    width: 'style',
    multiple: true,
    tags: true,
    createTag: function (tag) {
        var isNew = false;
        tag.term = tag.term.toLowerCase();
        console.log(tag.term);
        if(!search(tag.term, dataBase)){
            if(confirm("Are you sure you want to add this tag:" + tag.term)){
                dataBase.push({id:dataBase.length+1, text: tag.term});
                isNew = true;
                //Update the tags array server side through a post request
            }
        }
        return {
                    id: tag.term,
                    text: tag.term,
                    isNew : isNew
                };
    },
    tokenSeparators: [',', '.']
})
});

// Is tag in database?
function search(nameKey, myArray){
for (var i=0; i < myArray.length; i++) {
    if (myArray[i].text.toLowerCase() === nameKey.toLowerCase()) {
        return true
    }
}
return false
};