What can I do about a virus that's affecting my relatives even though they're in different places?

When I run into viruses on systems I didn't setup, this is what I do(In order)

  1. Boot to safe mode, login as user, run msconfig, look for any entries starting up in the users home directory. Those are probably a virus and can be removed.
  2. Boot to safe mode, Run MalwareBytes and scan for the malware.
  3. Grab the AVG rescue disc, boot from it. run a scan and replace/rename any files found to be infected. This is obviously the most difficult to deal with remotely.

When I setup a computer, the user gets two accounts Manager, and User. I explain to them they should use the "User" account and only use Manager to install software. In that case, if they get a virus, I have them logout, login as Manager, then run MalwareBytes, which finds and removes the virus in 98% of the cases I've seen.