two (or more) graphs in one plot with different x-axis AND y-axis scales in python

The idea would be to create three subplots at the same position. In order to make sure, they will be recognized as different plots, their properties need to differ - and the easiest way to achieve this is simply to provide a different label, ax=fig.add_subplot(111, label="1").

The rest is simply adjusting all the axes parameters, such that the resulting plot looks appealing. It's a little bit of work to set all the parameters, but the following should do what you need.

enter image description here

import matplotlib.pyplot as plt

x_values1=[1,2,3,4,5]
y_values1=[1,2,2,4,1]

x_values2=[-1000,-800,-600,-400,-200]
y_values2=[10,20,39,40,50]

x_values3=[150,200,250,300,350]
y_values3=[10,20,30,40,50]


fig=plt.figure()
ax=fig.add_subplot(111, label="1")
ax2=fig.add_subplot(111, label="2", frame_on=False)
ax3=fig.add_subplot(111, label="3", frame_on=False)

ax.plot(x_values1, y_values1, color="C0")
ax.set_xlabel("x label 1", color="C0")
ax.set_ylabel("y label 1", color="C0")
ax.tick_params(axis='x', colors="C0")
ax.tick_params(axis='y', colors="C0")

ax2.scatter(x_values2, y_values2, color="C1")
ax2.xaxis.tick_top()
ax2.yaxis.tick_right()
ax2.set_xlabel('x label 2', color="C1") 
ax2.set_ylabel('y label 2', color="C1")       
ax2.xaxis.set_label_position('top') 
ax2.yaxis.set_label_position('right') 
ax2.tick_params(axis='x', colors="C1")
ax2.tick_params(axis='y', colors="C1")

ax3.plot(x_values3, y_values3, color="C3")
ax3.set_xticks([])
ax3.set_yticks([])

plt.show()