SQL Profiler for Mac OS

No, but here's a few options:

Run a server-side trace. You don't get the Profiler GUI, but the good news is that this kind of tracing is faster. (Heck, I recommend this to folks even when they have Windows on the desktop.) SQL Server Central has a good Stairway to Server-side Tracing. Server-side traces can output to file or to table - I'd caution against writing the trace data into a table on the same server that you're monitoring because that'll have a performance impact.

Run Profiler in a VM. After all, if you're managing SQL Server, you probably need SQL Server Management Studio anyway, and that's still Windows-only. (That's how I manage SQL Server personally - I'm a Microsoft Certified Master of SQL Server, and I've been using Macs since the mid-2000s.)

Run sp_BlitzCache. The open source sp_BlitzCache analyzes the most resource-intensive queries in your plan cache - without starting a heavy-overhead trace or XE session. SQL Server is already gathering this data for you on every supported version/edition. Yes, right now, even as you're reading advice on a web site. You can run it from anything app runs T-SQL, like Microsoft's new cross-platform SQL Operations Studio. (Disclaimer: I'm one of the sp_BlitzCache authors.)

Use Extended Events instead. (This isn't really a solution, but I know someone's going to suggest it, so might as well get it out of the way. The Extended Events people are like vegans, crossfitters, and atheists: they can't wait to tell you about their religion.) Extended Events is the replacement for Profiler, but the thing is, if you're just getting started, you're going to want to use SSMS's excellent wizard for setting up a new XE session - meaning, you still need SSMS. There's also a "Profiler" extension for Azure Data Studio, but...that's actually Extended Events.

Get a third party monitoring tool. If you need to know what's happening on your SQL Server on a regular basis, this is usually more lightweight than running Profiler. Plus, they have way more smarts built in to tell you what's been happening.