Select all columns except one in MySQL?

(Do not try this on a big table, the result might be... surprising !)

TEMPORARY TABLE

DROP TABLE IF EXISTS temp_tb;
CREATE TEMPORARY TABLE ENGINE=MEMORY temp_tb SELECT * FROM orig_tb;
ALTER TABLE temp_tb DROP col_a, DROP col_f,DROP col_z;    #// MySQL
SELECT * FROM temp_tb;

DROP syntax may vary for databases @Denis Rozhnev

Actually there is a way, you need to have permissions of course for doing this ...

SET @sql = CONCAT('SELECT ', (SELECT REPLACE(GROUP_CONCAT(COLUMN_NAME), '<columns_to_omit>,', '') FROM INFORMATION_SCHEMA.COLUMNS WHERE TABLE_NAME = '<table>' AND TABLE_SCHEMA = '<database>'), ' FROM <table>');

PREPARE stmt1 FROM @sql;
EXECUTE stmt1;

Replacing <table>, <database> and <columns_to_omit>