PDF Blob - Pop up window not showing content

You need to set the responseType to arraybuffer if you would like to create a blob from your response data:

$http.post('/fetchBlobURL',{myParams}, {responseType: 'arraybuffer'})
   .success(function (data) {
       var file = new Blob([data], {type: 'application/pdf'});
       var fileURL = URL.createObjectURL(file);
       window.open(fileURL);
});

more information: Sending_and_Receiving_Binary_Data

If you set { responseType: 'blob' }, no need to create Blob on your own. You can simply create url based with response content:

$http({
    url: "...",
    method: "POST",
    responseType: "blob"
}).then(function(response) {
    var fileURL = URL.createObjectURL(response.data);
    window.open(fileURL);
});