Minimum of last k

I've done this, in fact, I'm using a no-optical MBP right now.

Here is my experience detailed in full.

Notes:

1. I put the SSD in the optical bay, since the HDD bay has vibration dampers and the optical bay solution I bought did not have anything close to what comes in the original HDD bay. The SSD has no vibration, so it's a good fit there.
2. I agree with Fishtoaster... see my link above for how I did it.
3. I have bootcamp and rEFIt installed, so when I boot, I get option for SSD Mac, HD Mac, or Windows... works pretty nicely.

May be able just create a simlink to the /User directory.

To do this, open up Terminal and enter:

cd [SeperateDrivePath*]
ln -s ./Users /Users

You'll want to move your original Users folder out of the way (rename it or move it or whatever).

*Where [SeperateDrivePath] is the path to your volume just underneath the cloned /Users folder. Probably something like /Volumes/Some Hard Drive Name/. In this case, your clones /Users should exist at/Volumes/Some Hard Drive Name/Users.