Is it possible to use visual studio performance profiling with service fabric?

What you're seeing is Visual Studio attempting to start your service host process on its own outside of the Service Fabric runtime. Normally, when you run a service through Visual Studio, you deploy the application project, which goes through the process of registering and instantiating your services on your local Service Fabric cluster.

Instrumentation currently doesn't work out-of-the-box with Service Fabric projects for this reason. We're looking at ways to make this possible in the future.

You can still do Sampling profiling, which allows you to attach the profiler to a running EXE. In that case, you'd deploy your application normally first, then attach the profiler to your service EXEs.