InvalidOperationException in Asp.Net MVC while using In-Memory Cache

You need to register IMemoryCache to Unity container

using Microsoft.Extensions.Caching.Memory;
using Microsoft.Extensions.Options;

UnityContainer container = new UnityContainer(); // your unity container

MemoryCacheOptions memoryCacheOptions = new MemoryCacheOptions
{
    //config your cache here
};

MemoryCache memoryCache = new MemoryCache(Options.Create<MemoryCacheOptions>(memoryCacheOptions));
container.RegisterInstance<IMemoryCache>(memoryCache);