HTML Table - Both fixed and multiple variable column widths

You could set the table-layout: fixed for the table element, then simply set width attribute on relevant <td> or <th> elements:

table {
    table-layout: fixed;
}

JSFiddle Demo.

From the MDN:

The table-layout CSS property defines the algorithm to be used to layout the table cells, rows, and columns.

Values:

fixed:
Table and column widths are set by the widths of table and col elements or by the width of the first row of cells. Cells in subsequent rows do not affect column widths.

to fixed width in a table, you need the table-layout propertie set to fixed; Since you mix % and px , it will not be coherent .

You may set only the px width and eventually a small value of % and let other column to use width left avalaible. example : http://jsfiddle.net/M4Et8/2/

<table style='table-layout:fixed;width:100%' border='1'>
    <tr>
        <th style='width: 20%;'>Column1</th>
        <th style='width: 100px;'>Column2</th>
        <th >Column3</th>
        <th style='width: 200px;'>Column4</th>
        <th >Column5</th>
    </tr>
</table>