How use async service into angular httpClient interceptor

I think that there is a issue about the reactive flow. The method intercept expects to return an Observable and you have to flatten your async result with the Observable returned by next.handle

Try this

intercept(req: HttpRequest<any>, next: HttpHandler): Observable<HttpEvent<any>> {
      return this.asyncService.applyLogic(req).mergeMap((modifiedReq)=> {
        const newReq = req.clone(modifiedReq);
        return next.handle(newReq);
    });
}

You could also use switchMap instead of mergeMap

Asynchronous operation in HttpInterceptor with Angular 6.0 and RxJS 6.0

auth.interceptor.ts

import { HttpInterceptor, HttpEvent, HttpHandler, HttpRequest } from '@angular/common/http';
import { Injectable } from '@angular/core';
import { Observable } from 'rxjs/index';;
import { switchMap } from 'rxjs/internal/operators';

@Injectable()
export class AuthInterceptor implements HttpInterceptor {

  constructor(private auth: AuthService) {}

  intercept(request: HttpRequest<any>, next: HttpHandler): Observable<HttpEvent<any>> {

    return this.auth.client().pipe(switchMap(() => {
        return next.handle(request);
    }));

  }
}

auth.service.ts

import { Injectable } from '@angular/core';
import { Observable } from 'rxjs';

@Injectable()
export class AuthService {

  constructor() {}

  client(): Observable<string> {
    return new Observable((observer) => {
      setTimeout(() => {
        observer.next('result');
      }, 5000);
    });
  }
}

If you need to invoke an async function within interceptor then the following approach can be followed using the rxjs from operator.

import { MyAuth} from './myauth'
import { from, lastValueFrom } from "rxjs";

@Injectable()
export class AuthInterceptor implements HttpInterceptor {
  constructor(private auth: MyAuth) {}

  intercept(req: HttpRequest<any>, next: HttpHandler) {
    // convert promise to observable using 'from' operator
    return from(this.handle(req, next))
  }

  async handle(req: HttpRequest<any>, next: HttpHandler) {
    // if your getAuthToken() function declared as "async getAuthToken() {}"
    await this.auth.getAuthToken()

    // if your getAuthToken() function declared to return an observable then you can use
    // await this.auth.getAuthToken().toPromise()

    const authReq = req.clone({
      setHeaders: {
        Authorization: authToken
      }
    })

    return await lastValueFrom(next.handle(req));
  }
}