How to use apply a custom drawable to RadioButton?

You should set android:button="@null" instead of "null".

You were soo close!

full solution here:

<RadioGroup
    android:id="@+id/radioGroup1"
    android:layout_width="wrap_content"
    android:layout_height="wrap_content" >

    <RadioButton
        android:id="@+id/radio0"
        android:layout_width="wrap_content"
        android:layout_height="wrap_content"
        android:button="@drawable/oragne_toggle_btn"
        android:checked="true"
        android:text="RadioButton" />

    <RadioButton
        android:id="@+id/radio1"
        android:layout_width="wrap_content"
        android:layout_height="wrap_content"
        android:button="@drawable/oragne_toggle_btn"
        android:layout_marginTop="20dp"
        android:text="RadioButton" />

    <RadioButton
        android:id="@+id/radio2"
        android:layout_width="wrap_content"
        android:layout_height="wrap_content"
        android:button="@drawable/oragne_toggle_btn"
        android:layout_marginTop="20dp"
        android:text="RadioButton" />
</RadioGroup>

selector XML

<?xml version="1.0" encoding="utf-8"?>
 <selector xmlns:android="http://schemas.android.com/apk/res/android">

<item android:drawable="@drawable/orange_btn_selected" android:state_checked="true"/>
<item android:drawable="@drawable/orange_btn_unselected"    android:state_checked="false"/>

 </selector>

Give your radiobutton a custom style:

<style name="MyRadioButtonStyle" parent="@android:style/Widget.CompoundButton.RadioButton">
    <item name="android:button">@drawable/custom_btn_radio</item>
</style>

custom_btn_radio.xml

<selector xmlns:android="http://schemas.android.com/apk/res/android">
    <item android:state_checked="true" android:state_window_focused="false"
          android:drawable="@drawable/btn_radio_on" />
    <item android:state_checked="false" android:state_window_focused="false"
          android:drawable="@drawable/btn_radio_off" />

    <item android:state_checked="true" android:state_pressed="true"
          android:drawable="@drawable/btn_radio_on_pressed" />
    <item android:state_checked="false" android:state_pressed="true"
          android:drawable="@drawable/btn_radio_off_pressed" />

    <item android:state_checked="true" android:state_focused="true"
          android:drawable="@drawable/btn_radio_on_selected" />
    <item android:state_checked="false" android:state_focused="true"
          android:drawable="@drawable/btn_radio_off_selected" />

    <item android:state_checked="false" android:drawable="@drawable/btn_radio_off" />
    <item android:state_checked="true" android:drawable="@drawable/btn_radio_on" />
</selector>

Replace the drawables with your own.