How to Create Multiple Where Clause Query Using Laravel Eloquent?

You can use subqueries in anonymous function like this:

 $results = User::where('this', '=', 1)
       ->where('that', '=', 1)
       ->where(
           function($query) {
             return $query
                    ->where('this_too', 'LIKE', '%fake%')
                    ->orWhere('that_too', '=', 1);
            })
            ->get();

In Laravel 5.3 (and still true as of 7.x) you can use more granular wheres passed as an array:

$query->where([
    ['column_1', '=', 'value_1'],
    ['column_2', '<>', 'value_2'],
    [COLUMN, OPERATOR, VALUE],
    ...
])

Personally I haven't found use-case for this over just multiple where calls, but fact is you can use it.

Since June 2014 you can pass an array to where

As long as you want all the wheres use and operator, you can group them this way:

$matchThese = ['field' => 'value', 'another_field' => 'another_value', ...];

// if you need another group of wheres as an alternative:
$orThose = ['yet_another_field' => 'yet_another_value', ...];

Then:

$results = User::where($matchThese)->get();

// with another group
$results = User::where($matchThese)
    ->orWhere($orThose)
    ->get();

The above will result in such query:

SELECT * FROM users
  WHERE (field = value AND another_field = another_value AND ...)
  OR (yet_another_field = yet_another_value AND ...)

Query scopes may help you to let your code more readable.

http://laravel.com/docs/eloquent#query-scopes

Updating this answer with some example:

In your model, create scopes methods like this:

public function scopeActive($query)
{
    return $query->where('active', '=', 1);
}

public function scopeThat($query)
{
    return $query->where('that', '=', 1);
}

Then, you can call this scopes while building your query:

$users = User::active()->that()->get();