How to click on span element with python selenium

Search by link text can help you only if your span is a child of anchor tag, e.g. <a><span style="vertical-align: middle;">No</span></a>. As you're trying to click it, I believe it's really inside an anchor, but if not I'd suggest you to use XPath with predicate that returns True only if exact text content matched:

//span[text()="No"]

Note that //span[contains(text(), "No")] is quite unreliable solution as it will return span elements with text

• "November rain"
• "Yes. No."
• "I think Chuck Norris can help you"

etc...

If you get NoSuchElementException you might need to wait for element to appear in DOM:

from selenium.webdriver.support import expected_conditions as EC
from selenium.webdriver.common.by import By
from selenium.webdriver.support.ui import WebDriverWait as wait

wait(driver, 10).until(EC.element_to_be_clickable((By.XPATH, "//span[text()='No']"))).click()