How to automatically reload a single modified window in Notepad++

Unless your file is very large, it is possible.

Check menu item View > Monitoring (tail -f)

• This setting is per file, so it will work for your individual file.
• The file is not editable when the setting is enabled.
• If you have enabled word wrapping and the file is not always scrolled to end as expected, update Notepad++ to version 7.9 where this issue is fixed.

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This is a workaround if the above won't satisfy you:

Copy your Notepad++ into another directory, configure global reload settings differently and keep your special file open in that second instance of Notepad++.

• You can even set a different color style for that instance so you can instantly recognize it.
• This is a good choice to keep the file editable for certain use cases.

Click the eyeball on later versions. Currently on 7.5.6 but not sure how far back the eyeball goes.