How do I get ASP.NET Web API to return JSON instead of XML using Chrome?

If you do this in the WebApiConfig you will get JSON by default, but it will still allow you to return XML if you pass text/xml as the request Accept header.

Note: This removes the support for application/xml

public static class WebApiConfig
{
    public static void Register(HttpConfiguration config)
    {
        config.Routes.MapHttpRoute(
            name: "DefaultApi",
            routeTemplate: "api/{controller}/{id}",
            defaults: new { id = RouteParameter.Optional }
        );

        var appXmlType = config.Formatters.XmlFormatter.SupportedMediaTypes.FirstOrDefault(t => t.MediaType == "application/xml");
        config.Formatters.XmlFormatter.SupportedMediaTypes.Remove(appXmlType);
    }
}

If you are not using the MVC project type and therefore did not have this class to begin with, see this answer for details on how to incorporate it.

Using RequestHeaderMapping works even better, because it also sets the Content-Type = application/json in the response header, which allows Firefox (with JSONView add-on) to format the response as JSON.

GlobalConfiguration.Configuration.Formatters.JsonFormatter.MediaTypeMappings
.Add(new System.Net.Http.Formatting.RequestHeaderMapping("Accept", 
                              "text/html",
                              StringComparison.InvariantCultureIgnoreCase,
                              true, 
                              "application/json"));

Note: Read the comments of this answer, it can produce a XSS Vulnerability if you are using the default error handing of WebAPI

I just add the following in App_Start / WebApiConfig.cs class in my MVC Web API project.

config.Formatters.JsonFormatter.SupportedMediaTypes
    .Add(new MediaTypeHeaderValue("text/html") );

That makes sure you get JSON on most queries, but you can get XML when you send text/xml.

If you need to have the response Content-Type as application/json please check Todd's answer below.

NameSpace is using System.Net.Http.Headers.

I like Felipe Leusin's approach best - make sure browsers get JSON without compromising content negotiation from clients that actually want XML. The only missing piece for me was that the response headers still contained content-type: text/html. Why was that a problem? Because I use the JSON Formatter Chrome extension, which inspects content-type, and I don't get the pretty formatting I'm used to. I fixed that with a simple custom formatter that accepts text/html requests and returns application/json responses:

public class BrowserJsonFormatter : JsonMediaTypeFormatter
{
    public BrowserJsonFormatter() {
        this.SupportedMediaTypes.Add(new MediaTypeHeaderValue("text/html"));
        this.SerializerSettings.Formatting = Formatting.Indented;
    }

    public override void SetDefaultContentHeaders(Type type, HttpContentHeaders headers, MediaTypeHeaderValue mediaType) {
        base.SetDefaultContentHeaders(type, headers, mediaType);
        headers.ContentType = new MediaTypeHeaderValue("application/json");
    }
}

Register like so:

config.Formatters.Add(new BrowserJsonFormatter());