How do I create a deb package for a single python script?

What follows is a basic example of how a source package for a python script might look. While most of the packaging tutorials are a bit complex, they can really help if you hit a problem. That said, I first learned the basics of Debian packaging by simply looking at Debian packages. apt-get source something similar and learn by example.

Here's your basic source package layout:

my-script/
    -- myScript
    -- debian/
        -- changelog
        -- copyright
        -- compat
        -- rules
        -- control
        -- install

Run dch --create in the directory to create a properly formatted debian/changelog entry.

debian/copyright should look like:

Format: http://www.debian.org/doc/packaging-manuals/copyright-format/1.0/
Upstream-Name: myScript
Upstream-Contact: Name, <email@address>

Files: *
Copyright: 2011, Name, <email@address>
License: (GPL-2+ | LGPL-2 | GPL-3 | whatever)
 Full text of licence.
 .
 Unless there is a it can be found in /usr/share/common-licenses

debian/compat can just be: 7

debian/rules:

#!/usr/bin/make -f

%:
    dh $@ --with python2

Note that there must be "tab" before dh $@ --with python2, not spaces.

debian/control:

Source: my-script
Section: python
Priority: optional
Maintainer: Name, <email@address>
Build-Depends: debhelper (>= 7),
               python (>= 2.6.6-3~)
Standards-Version: 3.9.2
X-Python-Version: >= 2.6


Package: my-script
Architecture: all
Section: python
Depends: python-appindicator, ${misc:Depends}, ${python:Depends}
Description: short description
 A long description goes here.
 .
 It can contain multiple paragraphs

debian/install:

myScript usr/bin/

This file indicates which file will be installed into which folder.

Now build it with debuild --no-tgz-check

This will create a functional deb package. Lintian is going to throw a few warnings regarding the lack of an orig.tar.gz, but unless you plan on creating a proper upstream project that makes tarball releases you'll probably just want to ignore that for now.

1. create a folder with any name on your home eg: mypyscript
2. Open the folder and create two folders with names 'DEBIAN' and 'usr'
3. Open the folder DEBIAN. Create a text file (without extension) with name 'control' there.

4. Open 'control' and type as follows and save it on DEBIAN

   Package: mypyscript
   Version: 0.01
   Architecture: all
   Maintainer: your name<your mail id>
   Installed-Size: 2
   Depends: python-appindicator
   Section: extras
   Priority: optional
   Homepage: your homepage
   Description: describe
   

5. Back to the folder named mypyscript. Open 'usr'. Create a folder named 'bin'. Open 'bin' and paste your pythonscript file there.

6. You can also make a menu entry. But that is not essential.
7. Back to the home folder where the folder 'mypyscript' lies or close the file browser.
8. Open terminal. Be sure that terminal is in the home folder. type dpkg -b mypyscript .Then press enter. In seconds your deb package is ready

note: please fill the 'control' file properly. Don't use apostrophes. It is only for indicating the names.

You could try with Debreate, a GUI tool for creating packages.