How can I hide columns in Openpyxl?

Columns can be grouped:

ws.column_dimensions.group(start='B', end='CU', hidden=True)

You can use a loop for a defined workbook wb. in this example I have 10 columns with data and want to hidden all the remaining 16385 is the index of the last excel column, XFD, +1.

import openpyxl as op

worksheet = wb['Sheet1']

max_column =ws.max_column

last_column = op.utils.cell.column_index_from_string('XFD')

for idx in range(max_column+1, last_column+1):
    ws.column_dimensions[op.utils.get_column_letter(idx)].hidden = True

if you know the positions of your columns then will be easy

You should set the hidden attribute to True:

 worksheet.column_dimensions['A'].hidden= True

In order to hide more than one column:

for col in ['A', 'B', 'C']:
    worksheet.column_dimensions[col].hidden= True