Android - Force Android to display in grayscale

Android 5.0 Lollipop provides this feature by default:

Enable Developer mode (by tapping build number within Settings > About phone multiple times)
Go to Developer Options and turn it on.
Under Hardware accelerated rendering you will see option called Simulate color space, click it and set it to Monochromacy.

A launcher will not put the whole system in grayscale, only your home screen.

The Samsung Galaxy S5 has a true grayscale function you can enable system wide.

If you don't want to buy a Samsung Galaxy S5 then try CF.Lumen https://play.google.com/store/apps/details?id=eu.chainfire.lumen

It can color the screen to a specific tint. As a side effect the battery life will increase a lot.

If you have a Samsung phone, but not necessarily the S5 then you can use this root app to put everything into true monochrome (grayscale):

https://play.google.com/store/apps/details?id=mobi.pruss.GalacticNight

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