Desktop notifications from content scripts

You can't show notifications directly through a content script. But, you can show them through the background page.

Your manifest.js should look something like this:

    {
     "name": "Notify This",
     "version": "0.1",
     "permissions": [
        "notifications"
     ],
     "background_page": "background.html",
     "content_scripts": [
       {
        "matches": ["http://www.example.com/*"],
        "js": ["contentscript.js"]
       }
     ]
    }    

Then use the chrome.extension.sendRequest():

    // in your contentscript.js
    chrome.extension.sendRequest({msg: "Sup?"}, function(response) { // optional callback - gets response
        console.log(response.returnMsg);
    });

And on the receiving end you should have a onRequest listener:

    // in your background.html
    chrome.extension.onRequest.addListener(
      function(request, sender, sendResponse) {

            // Create a simple text notification:
        var notify = webkitNotifications.createNotification(
          '48.png',  // icon url - can be relative
          'Hello!',  // notification title
          request.msg  // notification body text
        );

        notify.show();

        setTimeout(function(){ notify.cancel(); },5000);
        sendResponse({returnMsg: "All good!"}); // optional response
      });

Yes, notifications use Chrome specific API, and the content script is only valid for general javascript etc... The background page is where all chrome specific API's are capable of running... First you'll need to register your background page in the manifest.json file - like this:

 "background_page": "background.html",

Also in the manifest file, Allow the required permissions:

"permissions": [ "notifications" ],

Then your script in the background page should look like this :

<script>
setTimeout("setNotification();",1); 
function setNotification(){
  var n
  if (window.webkitNotifications.checkPermission() != 0){
    setNotification();
    return false;
  }
n = window.webkitNotifications.createHTMLNotification('http://www.your-notification-address.com');
n.show();}
</script>