Breakpoints not working on Android Studio 3.3

Found the answer with the help of @pskink. "If" statements are "invalid" locales for breakpoints. See the checkmarks below:

The issue is in the build tool chain (gradle, d8/r8). Problem is fixed in Android Studio 3.4 Beta 1 with gradle 3.4.0-beta01.

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Or a workaround solution for this issue can be used by locally updating the top-level build.gradle configuration for your project:

buildscript {
    repositories {
        maven {
            url 'http://storage.googleapis.com/r8-releases/raw' // ADD THIS.
        }
    }

    dependencies {
        classpath 'com.android.tools:r8:1.3.55'  // ADD THIS. Must be before the Gradle Plugin for Android.
        classpath 'com.android.tools.build:gradle:3.3'
    } 
}

Once the next point release of Android Gradle Plugins takes place these changes can be removed.

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For more information, see: https://issuetracker.google.com/issues/122450679